Document Detail

Hyperintense globus pallidus on T1-weighted MR imaging in acute kernicterus: is it common or rare?
MedLine Citation:
PMID:  15565320     Owner:  NLM     Status:  MEDLINE    
Globus pallidus involvement is a well-known magnetic resonance (MR) imaging finding of acute kernicterus. However, it is not clear how early the involvement of globus pallidus occurs and whether or not it is seen in every case. Therefore, we aimed to investigate the globus pallidus involvement in 13 neonates with acute kernicterus by MR imaging. Thirteen neonates who were admitted with jaundice, encephalopathy and indirect hyperbilirubinemia (mean, 37.0 mg/dl) were prospectively evaluated with cranial MR imaging. Pathological signal changes were noted concerning the globus pallidus. Eight of the 13 patients demonstrated bilateral, symmetric increased signal intensity in the globus pallidus on T1-weighted MR imaging. These lesions were not apparent on T2-weighted images. Multiple parenchymal punctuate T1 hyperintense lesions were detected in one patient without globus pallidus involvement. This appearance was consistent with hemorrhage. The MR imaging findings of the other four patients showed no evidence of abnormality. The symmetric involvement of globus pallidus seen as hyperintense on T1-weighted MR imaging is a common and characteristic finding of acute kernicterus.
Abdulhakim Coskun; Ali Yikilmaz; Sefer Kumandas; Okkes Ibrahim Karahan; Mustafa Akcakus; Ali Manav
Publication Detail:
Type:  Journal Article     Date:  2004-11-24
Journal Detail:
Title:  European radiology     Volume:  15     ISSN:  0938-7994     ISO Abbreviation:  Eur Radiol     Publication Date:  2005 Jun 
Date Detail:
Created Date:  2005-05-20     Completed Date:  2005-10-04     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9114774     Medline TA:  Eur Radiol     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  1263-7     Citation Subset:  IM    
Department of Radiology, Erciyes University Medical School, Kayseri, Turkey.
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MeSH Terms
Acute Disease
Globus Pallidus / pathology*
Infant, Newborn
Kernicterus / complications*
Magnetic Resonance Imaging / methods*
Prospective Studies

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