| Hyperinsulinism associated with gestational exposure to bupropion in a newborn infant. | |
| | |
MedLine Citation:
|
PMID: 22145484 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
|
This case report describes severe hyperinsulinism in a term newborn infant without typical perinatal risk factors for transient hyperinsulinism. The mother had received bupropion, an antidepressant and aid to smoking cessation, throughout pregnancy. The infant presented with profound hypoglycemia and seizures on the 3rd day of life. Laboratory investigation confirmed hyperinsulinism. Stable euglycemia could be achieved only after starting diazoxide. The infant was weaned from diazoxide by 10 weeks of age without recurrence of hypoglycemia, signifying the transient nature of hyperinsulinism. This is the first reported case of a potential association between maternal bupropion use during pregnancy and neonatal hyperinsulinism, and highlights the importance of close monitoring of similar infants. |
| | |
Authors:
|
Tate Gisslen; Brandon Nathan; Theodore Thompson; Raghavendra Rao |
Related Documents
:
|
20409714 - Nursing our microbiota: molecular linkages between bifidobacteria and milk oligosacchar... 10690574 - Human milk feeding of the micropremie. 6864564 - Compensatory increases in milk secretion in response to unilateral inhibition by colchi... 8408724 - Excretion of lignocaine and its metabolite monoethylglycinexylidide in breast milk foll... 20698474 - Learning perceptual organization in infancy: the effect of simultaneous versus sequenti... 16763904 - Newborn screening for medium-chain acyl-coa dehydrogenase deficiency: a global perspect... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Journal of pediatric endocrinology & metabolism : JPEM Volume: 24 ISSN: 0334-018X ISO Abbreviation: J. Pediatr. Endocrinol. Metab. Publication Date: 2011 |
Date Detail:
|
Created Date: 2011-12-07 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9508900 Medline TA: J Pediatr Endocrinol Metab Country: England |
Other Details:
|
Languages: eng Pagination: 819-22 Citation Subset: IM |
Affiliation:
|
Department of Pediatrics, Division of Neonatology, University of Minnesota, Minneapolis 55455, MN, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Unique concurrent appearance of two rare conditions in a young girl: central precocious puberty due ...
Next Document: Child abuse suspicion masquerading new onset insulin dependent diabetes mellitus.