Document Detail

Hyperinsulinaemic hypoglycaemia in preterm neonates.
MedLine Citation:
PMID:  14711860     Owner:  NLM     Status:  MEDLINE    
Hyperinsulinism in infancy (HI) is an important cause of severe and recurrent hypoglycaemia in newborn infants. It usually appears in infants born at term, and only one case of its occurrence in a prematurely born infant has been reported as an incidental finding. This is a report of seven infants born at 31-36 weeks gestation who experienced severe persistent hyperinsulinism. Two infants were large for dates. All infants were difficult to manage, suggesting that the occurrence of HI with prematurity may be associated with a particularly aggressive illness. HI should be considered in the differential diagnosis of severe hypoglycaemia in preterm infants.
K Hussain; A Aynsley-Green
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Archives of disease in childhood. Fetal and neonatal edition     Volume:  89     ISSN:  1359-2998     ISO Abbreviation:  Arch. Dis. Child. Fetal Neonatal Ed.     Publication Date:  2004 Jan 
Date Detail:
Created Date:  2004-01-08     Completed Date:  2004-02-12     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  9501297     Medline TA:  Arch Dis Child Fetal Neonatal Ed     Country:  England    
Other Details:
Languages:  eng     Pagination:  F65-7     Citation Subset:  AIM; IM    
London Centre for Paediatric Endocrinology and Metabolism, Great Ormond Street Hospital for Children NHS Trust, London WC1N 3JH, UK.
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MeSH Terms
Birth Weight
Chlorothiazide / therapeutic use
Diazoxide / therapeutic use
Glucose / administration & dosage
Hyperinsulinism / blood,  complications*
Hypoglycemia / blood,  etiology*,  therapy
Infant, Newborn
Infant, Premature, Diseases / blood,  etiology*,  immunology,  therapy
Sodium Chloride Symporter Inhibitors / therapeutic use
Reg. No./Substance:
0/Diuretics; 0/Sodium Chloride Symporter Inhibitors; 364-98-7/Diazoxide; 50-99-7/Glucose; 58-94-6/Chlorothiazide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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