Document Detail


Hyperimmunoglobulin E syndrome associated with nephrotic syndrome.
MedLine Citation:
PMID:  10411355     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A 21-year-old man was admitted to Kure National Hospital with nephrotic syndrome in September 1996. He had suffered from an intractable pruritic skin rash and recurrent subcutaneous abscesses caused by the hyperimmunoglobulin E syndrome since the age of 18 months. Renal biopsy gave a diagnosis of membranoproliferative glomerulonephritis. Steroid therapy decreased urinary protein loss and hypoproteinemia, and his pruritic skin rash was improved. Patients with hyperimmunoglobulin E syndrome have a defective immune response, especially to Staphylococcus aureus infection. Continuous antigen stimulation may have caused this patient's renal histological damage as in immune complex glomerulonephritis.
Authors:
C Tanji; N Yorioka; K Kanahara; T Naito; H Oda; K Ishikawa; T Taguchi
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  38     ISSN:  0918-2918     ISO Abbreviation:  Intern. Med.     Publication Date:  1999 Jun 
Date Detail:
Created Date:  1999-08-24     Completed Date:  1999-08-24     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  JAPAN    
Other Details:
Languages:  eng     Pagination:  491-4     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine, Kure National Hospital.
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MeSH Terms
Descriptor/Qualifier:
Adult
Anticoagulants / therapeutic use
Biopsy
Diagnosis, Differential
Dilazep / therapeutic use
Drug Therapy, Combination
Follow-Up Studies
Glomerulonephritis, Membranoproliferative / complications,  drug therapy,  pathology
Glucocorticoids / therapeutic use
Humans
Job's Syndrome / complications*,  drug therapy,  pathology
Male
Nephrotic Syndrome / drug therapy,  etiology*,  pathology
Prednisolone / therapeutic use
Vasodilator Agents / therapeutic use
Warfarin / therapeutic use
Chemical
Reg. No./Substance:
0/Anticoagulants; 0/Glucocorticoids; 0/Vasodilator Agents; 35898-87-4/Dilazep; 50-24-8/Prednisolone; 81-81-2/Warfarin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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