| Hyperhomocystinemia in patients with nonarteritic anterior ischemic optic neuropathy, central retinal artery occlusion, and central retinal vein occlusion. | |
| | |
MedLine Citation:
|
PMID: 10919914 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
OBJECTIVE: This study aimed to determine the prevalence of hyperhomocystinemia among patients with nonarteritic anterior ischemic optic neuropathy (NAION), central retinal artery occlusion (CRAO), or central retinal vein occlusion (CRVO). DESIGN: Retrospective, case-control study. PARTICIPANTS: The study cohort consisted of 74 consecutive patients with NAION, CRAO, or CRVO who were examined at the Retina or Neuro-ophthalmological Unit of the Tel-Aviv Sourasky Medical Center from 1998 through 1999. The control group consisted of 81 consecutive patients of similar gender and age with no history of these pathologic conditions. MAIN OUTCOME MEASURES: Plasma homocystine levels of all study participants were obtained. RESULTS: Eighteen of 40 patients (45%) with NAION and eight of 13 patients (61.5%) with CRAO had hyperhomocystinemia compared with three of 21 (14.3%) in the CRVO group (P < 0.001) and eight (9.8%) in the control group (P < 0.0001). Hypertension and ischemic heart disease were significantly more prevalent in the NAION patients with elevated plasma homocystine. CONCLUSIONS: Our findings suggest that hyperhomocystinemia is a risk factor for NAION and CRAO. |
| | |
Authors:
|
P Pianka; Y Almog; O Man; M Goldstein; B A Sela; A Loewenstein |
Related Documents
:
|
20602324 - Morphologic changes and functional retinal impairment in patients with parkinson diseas... 11521694 - Incidental retinal phototoxicity associated with ingestion of photosensitizing drugs. 11922704 - The neurological abnormalities and operative findings in the transcallosal approach for... 10431794 - Solar retinopathy. a study from nepal and from germany. 10342594 - Treatment of seizures in subcortical laminar heterotopia with corpus callosotomy and la... 22101994 - Syncope and autonomic cardiovascular dysfunction in parkinson disease. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Ophthalmology Volume: 107 ISSN: 0161-6420 ISO Abbreviation: Ophthalmology Publication Date: 2000 Aug |
Date Detail:
|
Created Date: 2000-08-08 Completed Date: 2000-08-08 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 7802443 Medline TA: Ophthalmology Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 1588-92 Citation Subset: IM |
Affiliation:
|
Department of Ophthalmology, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel. boazp@netvision.net.il |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Aged Arteritis / complications Case-Control Studies Female Homocysteine / blood Humans Hyperhomocysteinemia / blood, complications* Male Middle Aged Optic Neuropathy, Ischemic / blood, complications* Prevalence Retinal Artery Occlusion / blood, complications* Retinal Vein Occlusion / blood, complications* Retrospective Studies Risk Factors |
| Chemical | |
Reg. No./Substance:
|
454-28-4/Homocysteine |
| Comments/Corrections | |
Comment In:
|
Ophthalmology. 2001 Aug;108(8):1363
[PMID:
11470665
]
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Topography-driven photorefractive keratectomy: results of corneal interactive programmed topographic...
Next Document: The prevalence of age-related maculopathy: the visual impairment project.