| Hyperhemolysis Syndrome Complicating Pregnancy in Homozygous δβ-Thalassemia. | |
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MedLine Citation:
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PMID: 22239462 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Hyperhemolysis syndrome in patients with sickle cell disease who are given compatible blood has been well described in the literature but a similar condition complicating pregnancy in β-thalassemia (β-thal) has not been reported. Pregnancy itself or continuation of blood transfusions can further exacerbate the condition which may become life-threatening. The exact mechanism of hyperhemolysis is not well understood. A bystander hemolysis mechanism has been proposed. Treatment with steroids, immunoglobulins and cyclosporin can be life saving. |
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Authors:
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Joseph Mechery; Kehinde Abidogun; Fiona Crosfill; James Jip |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-12 |
Journal Detail:
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Title: Hemoglobin Volume: - ISSN: 1532-432X ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-13 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7705865 Medline TA: Hemoglobin Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Obstetrics and Gynaecology, Royal Preston Hospital , Preston, Lancashire , UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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