| Hyperglycemic nonketotic states and other metabolic imbalances. | |
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MedLine Citation:
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PMID: 21496588 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Hemichorea and generalized chorea are well-recognized syndromes associated with nonketotic hyperglycemia. This condition usually occurs in older age, affects females more than men, and often heralds a new diagnosis of diabetes, usually type 2. It may resolve over days with treatment of the underlying hyperglycemia or persist for years. Magnetic resonance imaging is very characteristic, and shows T1 hyperdensity in the striatum. The underlying pathophysiology is not clear, but recent evidence suggests that the imaging may represent zinc, as opposed to calcium. Tetrabenazine has worked well when symptomatic treatment is required. Other rare causes of metabolic choreas include hypoparathyroid abnormalities, hypoglycemia, and hypernatremia. |
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Authors:
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William G Ondo |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Handbook of clinical neurology / edited by P.J. Vinken and G.W. Bruyn Volume: 100 ISSN: 0072-9752 ISO Abbreviation: Handb Clin Neurol Publication Date: 2011 |
Date Detail:
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Created Date: 2011-04-18 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0166161 Medline TA: Handb Clin Neurol Country: Netherlands |
Other Details:
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Languages: eng Pagination: 287-91 Citation Subset: IM |
Copyright Information:
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Copyright © 2011 Elsevier B.V. All rights reserved. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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