Document Detail


Hyperglycemia and outcome after myocardial infarction and cardiac surgery: so what?
MedLine Citation:
PMID:  16959754     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Hyperglycemia is a frequent observation during acute illness such as myocardial infarction and after major surgery. The proportion of patients with hyperglycemia may be as high as 95% to 100% after cardiac surgery. This stress-induced hyperglycemia has a detrimental effect on outcome after myocardial infarction and cardiac surgery. Mortality may increase by a factor of 4, especially in non-diabetic patients. Control of hyperglycemia to normalize blood glucose is associated with a clear clinical benefit. This effect is most beneficial in nondiabetic patients with hyperglycemia. The exact target level of glycemia is still a matter of investigation, but normalization to values between 80 and 125 mg/dL is probably optimal.
Authors:
Michael J Hiesmayr
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Seminars in cardiothoracic and vascular anesthesia     Volume:  10     ISSN:  1089-2532     ISO Abbreviation:  Semin Cardiothorac Vasc Anesth     Publication Date:  2006 Sep 
Date Detail:
Created Date:  2006-09-08     Completed Date:  2007-01-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9807630     Medline TA:  Semin Cardiothorac Vasc Anesth     Country:  United States    
Other Details:
Languages:  eng     Pagination:  220-3     Citation Subset:  IM    
Affiliation:
Department of Cardiac-Thoracic-Vascular Anaesthesia & Intensive Care Medicine, Medical University Vienna, Vienna, Austria. michael.hiesmayr@meduniwien.ac.at
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MeSH Terms
Descriptor/Qualifier:
Cardiac Surgical Procedures / adverse effects*
Comorbidity
Humans
Hyperglycemia / drug therapy,  epidemiology*,  etiology
Insulin / therapeutic use
Myocardial Infarction / drug therapy,  epidemiology*
Thoracic Surgery
Chemical
Reg. No./Substance:
11061-68-0/Insulin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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