Document Detail

Hypergammaglobulinemic purpura of Waldenstrom associated with systemic lupus erythematosus: report of a case and review of the literature.
MedLine Citation:
PMID:  7539322     Owner:  NLM     Status:  MEDLINE    
A patient with hyperglobulinemic purpura of Waldenstrom and systemic lupus erythematosus is reported. The coexistence of these two conditions which share a number of common clinical and laboratory features is rare. Treatment of the patient with prednisone, colchicine and hydroxychloroquine led to the improvement of the cutaneous vasculitis and a drop in ESR, serum gamma globulins and IgM and IgG rheumatoid factors. The features of nine other cases and the immunopathogenesis of the disease are reviewed.
G S Habib; M M Stimmer; F P Quismorio
Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Lupus     Volume:  4     ISSN:  0961-2033     ISO Abbreviation:  Lupus     Publication Date:  1995 Feb 
Date Detail:
Created Date:  1995-07-05     Completed Date:  1995-07-05     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9204265     Medline TA:  Lupus     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  19-22     Citation Subset:  IM    
University of Southern California, Department of Medicine, Los Angeles, USA.
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MeSH Terms
Colchicine / therapeutic use
Hydroxychloroquine / therapeutic use
Immunoglobulin G / blood
Immunoglobulin M / blood
Lupus Erythematosus, Systemic / blood,  complications*,  drug therapy
Prednisone / therapeutic use
Rheumatoid Factor / blood
Skin / blood supply
Vasculitis / therapy
Waldenstrom Macroglobulinemia / blood,  complications*,  drug therapy
gamma-Globulins / metabolism
Reg. No./Substance:
0/Immunoglobulin G; 0/Immunoglobulin M; 0/gamma-Globulins; 118-42-3/Hydroxychloroquine; 53-03-2/Prednisone; 64-86-8/Colchicine; 9009-79-4/Rheumatoid Factor

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