| Hypereosinophilic syndrome with cardiac involvement in a pregnant patient with multiple sclerosis. | |
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MedLine Citation:
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PMID: 21494528 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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In hypereosinophilic syndrome, the sustained overproduction of eosinophils leads to the dysfunction of one or more organs. Symptoms vary in accordance with which organ is affected. Cardiac involvement leads to substantial morbidity and to most of the deaths that are associated with hypereosinophilic syndrome.Herein, we present the case of a 31-year-old woman, pregnant for 12 weeks and with a history of multiple sclerosis, who presented with transient vision loss and splinter hemorrhages in her fingernail beds. The diagnosis was hypereosinophilic syndrome with cardiac involvement. Echocardiography revealed 2 echodense structures: one that obliterated the left ventricular apex, and another in the basal lateral wall. The patient underwent therapy with prednisone and heparin but developed heparin-induced thrombocytopenia. This condition resolved when argatroban was substituted for heparin. Two weeks after the patient's release from the hospital, echocardiography revealed improvement in the echodense ventricular structures. The transient vision loss and the splinter hemorrhages were attributed to the hypereosinophilic syndrome.We believe that this is the 1st report of a pregnant patient with hypereosinophilic syndrome and cardiac involvement. |
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Authors:
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Amir Darki; Preeti P Kodali; John P McPheters; Harkiran Virk; Minesh R Patel; William Jacobs |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Texas Heart Institute journal / from the Texas Heart Institute of St. Luke's Episcopal Hospital, Texas Children's Hospital Volume: 38 ISSN: 1526-6702 ISO Abbreviation: Tex Heart Inst J Publication Date: 2011 |
Date Detail:
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Created Date: 2011-04-15 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8214622 Medline TA: Tex Heart Inst J Country: United States |
Other Details:
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Languages: eng Pagination: 163-5 Citation Subset: IM |
Affiliation:
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From: Divisions of Cardiology (Drs. Darki and Jacobs) and Internal Medicine (Drs. Kodali, McPheters, Patel, and Virk), Loyola University Medical Center, Maywood, Illinois 60153. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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