Document Detail

Hypereosinophilic syndrome associated with ulcerative colitis presenting with recurrent Loeffler's endocarditis and left ventricular thrombus treated successfully with immune suppressive therapy and anticoagulation.
MedLine Citation:
PMID:  24014425     Owner:  NLM     Status:  In-Data-Review    
We reported a case of a 28-year-old Caucasian woman with hypereosinophilic syndrome (HES) associated with ulcerative colitis who presented on separate occasions with Loeffler's endocarditis. She was admitted in 2008 with fever, headache, confusion and visual loss. Diagnostic workup uncovered an eosinophilia of 3.1×10(9)/L and major ECG abnormalities. Subsequent echocardiography revealed left ventricular wall motion abnormalities with mural thrombus. MRI brain scan showed multiple white matter lesions consistent with acute infarcts. She recovered rapidly with corticosteroids and anticoagulation. Four years later she re-presented with headache, fatigue and an eosinophilia of 13.4×10(9)/L. This occurred 3 months after cessation of immunosuppression and within 12 months of total colectomy for fulminant ulcerative colitis. Echocardiography was suggestive of hypereosinophilic endomyocardial fibrosis with left ventricular thrombus. Anticoagulation and corticosteroids were resumed with good effect. This report highlights the findings, treatment and outcome of ulcerative colitis-associated HES manifesting as recurrent Loeffler's endocarditis.
Srikanth Koneru; George Koshy; Colin Sharp; Alhossain A Khalafallah
Related Documents :
3121335 - Residual coronary stenosis after thrombolysis with rt-pa or streptokinase: acute result...
8891805 - Magnesium therapy, fibrinolytic parameters and von willebrand factor in acute myocardia...
17670355 - Does magnesium prophylaxis reduce the incidence of atrial fibrillation following corona...
3514485 - Clinical effects and kinetic properties of intravenous apsac--anisoylated plasminogen-s...
11850305 - Heart failure in older people: causes, diagnosis and treatment.
25489725 - Papp-a and igfbp-4 fragment levels in patients with st-elevation myocardial infarction ...
Publication Detail:
Type:  Journal Article     Date:  2013-09-05
Journal Detail:
Title:  BMJ case reports     Volume:  2013     ISSN:  1757-790X     ISO Abbreviation:  BMJ Case Rep     Publication Date:  2013  
Date Detail:
Created Date:  2013-09-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101526291     Medline TA:  BMJ Case Rep     Country:  England    
Other Details:
Languages:  eng     Pagination:  -     Citation Subset:  IM    
Department of Cardiology, Launceston General Hospital, Launceston, Tasmania, Australia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Does bone resorption stimulate periosteal expansion? A cross-sectional analysis of ?-C-telopeptides ...
Next Document:  Evidence for dysregulation of genome-wide recombination in oocytes with nondisjoined chromosomes 21.