| Hypercoagulable States. | |
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MedLine Citation:
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PMID: 21047574 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Hypercoagulable states can be inherited or acquired. Inherited hypercoagulable states can be caused by a loss of function of natural anticoagulant pathways or a gain of function in procoagulant pathways. Acquired hypercoagulable risk factors include a prior history of thrombosis, obesity, pregnancy, cancer and its treatment, antiphospholipid antibody syndrome, heparin-induced thrombocytopenia, and myeloproliferative disorders. Inherited hypercoagulable states combine with acquired risk factors to establish the intrinsic risk of venous thromboembolism for each individual. Venous thromboembolism occurs when the risk exceeds a critical threshold. Often a triggering factor, such as surgery, pregnancy, or estrogen therapy, is required to increase the risk above this critical threshold. |
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Authors:
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Julia A M Anderson; Jeffrey I Weitz |
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Publication Detail:
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Type: Journal Article Date: 2010-08-11 |
Journal Detail:
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Title: Clinics in chest medicine Volume: 31 ISSN: 1557-8216 ISO Abbreviation: Clin. Chest Med. Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-11-04 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7907612 Medline TA: Clin Chest Med Country: United States |
Other Details:
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Languages: eng Pagination: 659-73 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Department of Clinical and Laboratory Hematology, Royal Infirmary of Edinburgh, Scotland EH16 4SA, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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