Document Detail


Hypercalcemic crisis: A Clinical Review.
MedLine Citation:
PMID:  25447624     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Hypercalcemia is a common metabolic perturbation. However, hypercalcemic crisis is an unusual endocrine emergency, with little clinical scientific data to support therapeutic strategy. We review the relevant scientific English literature on the topic and review current management strategies after conducting a PubMed, MEDLINE and Google Scholar search for articles published between 1930 and June 2014 using specific keywords: hypercalcemic crisis, hyperparathyroid crisis, parathyroid storm, severe primary hyperparathyroidism, acute hyperparathyroidism and severe hypercalcemia for articles pertaining to the diagnosis, epidemiology, clinical presentation and treatment strategies. Despite extensive clinical experience, large and well-designed clinical studies to direct appropriate clinical care are lacking. Nonetheless, morbidity and mortality rates have dramatically declined since early series reported almost universal fatality. Improved outcomes can be attributed to modern diagnostic capabilities; leading to earlier diagnosis, along with the recognition that primary hyperparathyroidism is the most common etiology for hypercalcemic crisis. Hypercalcemic crisis is an unusual endocrine emergency that portends excellent outcomes if rapid diagnosis, medical treatment and definitive surgical treatment are expedited.
Authors:
Shazia Ahmad; Gayatri Kuraganti; Devin Steenkamp
Related Documents :
22964344 - Clinical recovery of chronic intestinal pseudo-obstruction with cisapride in a complex ...
23514324 - Peripapillary choroidal neovascularization in pars planitis.
23741224 - Tracheal adenocarcinoma treated with adjuvant radiation: a case report and literature r...
23119384 - A rare case of primary ewings sarcoma of the nasal bone.
22152904 - Sigmoid perforation and bucket-handle tear of the mesocolon after bicycle handlebar inj...
7000334 - Familial carotid body tumors: case report and epidemiologic review.
Publication Detail:
Type:  REVIEW     Date:  2014-10-17
Journal Detail:
Title:  The American journal of medicine     Volume:  -     ISSN:  1555-7162     ISO Abbreviation:  Am. J. Med.     Publication Date:  2014 Oct 
Date Detail:
Created Date:  2014-12-2     Completed Date:  -     Revised Date:  2014-12-3    
Medline Journal Info:
Nlm Unique ID:  0267200     Medline TA:  Am J Med     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Elsevier Inc. All rights reserved.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Etiologic and Therapeutic Analysis in Patients with Hypokalemic Non-periodic Paralysis.
Next Document:  Management of Nipple Discharge and the Associated Imaging Findings.