Document Detail

Hypercalcemia associated with eosinophilic myocarditis in a patient undergoing maintenance hemodialysis.
MedLine Citation:
PMID:  23064567     Owner:  NLM     Status:  In-Data-Review    
A 77-year-old man previously treated with maintenance hemodialysis was admitted due to appetite loss, nausea and shortness of breath. He showed progressive heart failure and eosinophilia without any basal disorders and was diagnosed with idiopathic hypereosinophilic syndrome (HES) accompanied by eosinophilic myocarditis. Laboratory data revealed hypercalcemia, a low serum parathyroid hormone level and a high 1,25(OH)(2)D concentration in spite of renal failure and no causal medications. Steroid therapy resulted in the patient's rapid recovery from heart failure, hypereosinophilia and hypercalcemia. Since the serum 1,25(OH)(2)D level promptly and markedly decreased, the hypercalcemia complicated with HES was most likely caused by extrarenal production of 1,25(OH)(2)D.
Ken-Ichiro Tanaka; Shozo Yano; Keisuke Okuyama; Masatake Sato; Mika Yamauchi; Toru Yamaguchi; Kazuaki Tanabe; Yasutoshi Himeno; Toshitsugu Sugimoto
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Publication Detail:
Type:  Journal Article     Date:  2012-10-15
Journal Detail:
Title:  Internal medicine (Tokyo, Japan)     Volume:  51     ISSN:  1349-7235     ISO Abbreviation:  Intern. Med.     Publication Date:  2012  
Date Detail:
Created Date:  2012-10-15     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9204241     Medline TA:  Intern Med     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  2913-6     Citation Subset:  IM    
Department of Internal Medicine 1, Shimane University Faculty of Medicine, Japan.
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