| Hyperacute therapies for childhood stroke: a case report and review of the literature. | |
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MedLine Citation:
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PMID: 21152213 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Objective. The optimal management of pediatric patients with arterial ischemic stroke (AIS) is not known. Despite this, goal-oriented, time-sensitive therapies geared to rapid reestablishment of arterial blood flow are occasionally applied with beneficial effects. The inconsistent approach to AIS is in part due to a lack of knowledge and preparedness. Methods. Case report of a 12-year-old male with right middle cerebral artery (MCA) occlusion resulting in dense left hemiplegia and mutism and review of the literature. Intervention(s). Mechanical thrombectomy, intra-arterial administration of rt-PA, vasodilators, and platelet inhibitors, and systemic anticoagulation and subsequent critical care support. Results. Restoration of right MCA blood flow and complete resolution of neurologic deficits. Conclusion. We report the gratifying outcome of treatment of a case of AIS in a pediatric patient treated with hyperacute therapies geared to arterial recanalization and subsequent neurologic critical care and review the pertinent literature. Guidelines for the emergency room management of pediatric AIS from prospective, randomized trials are needed. |
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Authors:
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Jose Irazuzta; Kevin J Sullivan |
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Publication Detail:
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Type: Journal Article Date: 2010-08-19 |
Journal Detail:
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Title: Neurology research international Volume: 2010 ISSN: 2090-1860 ISO Abbreviation: Neurol Res Int Publication Date: 2010 |
Date Detail:
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Created Date: 2010-12-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101543314 Medline TA: Neurol Res Int Country: United States |
Other Details:
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Languages: eng Pagination: 497326 Citation Subset: - |
Affiliation:
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Division of Pediatric Critical Care Medicine, University of Florida Health Science Center at Jacksonville and The Wolfson Children's Hospital, 800 Prudential Drive, Jacksonville, FL 32207, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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