Document Detail

Hyperacusis in patients with complex regional pain syndrome related dystonia.
MedLine Citation:
PMID:  17470470     Owner:  NLM     Status:  MEDLINE    
INTRODUCTION: In complex regional pain syndrome type 1 (CRPS-1), patients may have manifestations of central involvement, including allodynia, hyperalgesia or dystonia. We noted that more severely affected patients may experience hyperacusis, which may also reflect central involvement. The aim of this study was to evaluate the occurrence and characteristics of hyperacusis in patients with CRPS related dystonia.
METHODS: The presence of hyperacusis, speech reception thresholds (SRT), pure-tone thresholds (PTT) and uncomfortable loudness (UCL) was evaluated in 40 patients with CRPS related dystonia.
RESULTS: PTT and SRT were normal for all patients. 15 patients (38%) reported hyperacusis and this was associated with allodynia/hyperalgesia and with more affected extremities. UCLs of patients with hyperacusis were significantly lower than UCLs of patients without hyperacusis.
CONCLUSION: Hyperacusis is common among severely affected patients with CRPS related dystonia and may indicate that the disease spreads beyond those circuits related to sensory-motor processing of extremities.
M J M de Klaver; M A van Rijn; J Marinus; W Soede; J A P M de Laat; J J van Hilten
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-04-30
Journal Detail:
Title:  Journal of neurology, neurosurgery, and psychiatry     Volume:  78     ISSN:  1468-330X     ISO Abbreviation:  J. Neurol. Neurosurg. Psychiatr.     Publication Date:  2007 Dec 
Date Detail:
Created Date:  2007-11-20     Completed Date:  2007-12-10     Revised Date:  2013-06-06    
Medline Journal Info:
Nlm Unique ID:  2985191R     Medline TA:  J Neurol Neurosurg Psychiatry     Country:  England    
Other Details:
Languages:  eng     Pagination:  1310-3     Citation Subset:  IM    
Department of Neurology, Leiden University Medical Centre, PO Box 9600, Leiden, The Netherlands.
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MeSH Terms
Audiometry, Pure-Tone
Auditory Threshold / physiology
Dystonia / epidemiology*,  etiology*
Hyperacusis / diagnosis,  epidemiology*,  physiopathology
Hyperalgesia / epidemiology
Pain Measurement
Reflex Sympathetic Dystrophy / complications*,  diagnosis,  epidemiology*
Severity of Illness Index

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