Document Detail

Hyper-response and delay in the electroretinogram in acute ischemia.
MedLine Citation:
PMID:  6883195     Owner:  NLM     Status:  MEDLINE    
Acute ischemia was induced in 11 adult albino rabbits by clamping the retrobulbar blood vessels and in 5 others by raising the intraocular pressure. Total ischemia was achieved by raising the pressure in the hydraulic remote control system until total collapse of the retinal circulation was observed by indirect ophthalmoscopy and the response on the electroretinogram (ERG) disappeared. The level of ischemia was increased by 15% increments from 25% to 100%, and ERGs were recorded with a constant intensity of stimulation. The amplitude increased up to a peak at 55% ischemia, then decreased to extinction at 100% ischemia. The time of response increased to a maximum at 100% ischemia. The tentative conclusion is drawn that it is important to appreciate that ischemia, and not just degeneration, can cause a delay of the ERG response in humans.
J R Brunette; P Olivier; C Galeano; G Lafond
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Canadian journal of ophthalmology. Journal canadien d'ophtalmologie     Volume:  18     ISSN:  0008-4182     ISO Abbreviation:  Can. J. Ophthalmol.     Publication Date:  1983 Jun 
Date Detail:
Created Date:  1983-10-28     Completed Date:  1983-10-28     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0045312     Medline TA:  Can J Ophthalmol     Country:  CANADA    
Other Details:
Languages:  eng     Pagination:  188-93     Citation Subset:  IM    
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MeSH Terms
Eye / blood supply*
Ischemia / physiopathology*
Time Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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