Document Detail

Hyper-IgE syndrome: dental implications.
MedLine Citation:
PMID:  22769403     Owner:  NLM     Status:  In-Data-Review    
Hyper-IgE syndrome (HIES) is a rare multisystem disorder with both immunologic and nonimmunological features. It is characterized by extremely elevated IgE serum levels, eczema, and recurrent skin and pulmonary infections. Dental anomalies are often included, such as retention of deciduous teeth together with ectopic eruption or noneruption of permanent teeth. Severe susceptibility to caries and mycotic infections, insufficient transversal diameter of the palate, mucosal plaques, and fissures typically located on the tongue and on the palate are often present. The aim of this study was to review the literature and to report a 6-year observation of 6 patients with HIES (aged 8-39 years) with focus on their oral problems and the treatment provided. The importance of the role of the dentist both in early diagnosis of this syndrome and in monitoring oral conditions was stressed. The dentist can prevent infective complications and intercept the development of malocclusion with a reduction of the need for complex treatment.
Luca Esposito; Laura Poletti; Cinzia Maspero; Alessandro Porro; Maria Cristina Pietrogrande; Paola Pavesi; Rosa Maria Dellepiane; Giampietro Farronato
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Oral surgery, oral medicine, oral pathology and oral radiology     Volume:  114     ISSN:  2212-4411     ISO Abbreviation:  Oral Surg Oral Med Oral Pathol Oral Radiol     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-07-09     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101576782     Medline TA:  Oral Surg Oral Med Oral Pathol Oral Radiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  147-53     Citation Subset:  D; IM    
Copyright Information:
Copyright © 2012 Mosby, Inc. All rights reserved.
Assistant Professor, Department of Orthodontics, IRCCS Cà Granda - Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
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