Document Detail


HypC, the anthrone oxidase involved in aflatoxin biosynthesis.
MedLine Citation:
PMID:  20348292     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
On the basis of gene disruption and enzyme activity, hypC, an open reading frame in the region between the pksA (aflC) and nor-1 (aflD) genes in the aflatoxin biosynthesis gene cluster, encodes a 17-kDa oxidase that converts norsolorinic acid anthrone to norsolorinic acid.
Authors:
Kenneth C Ehrlich; Ping Li; Leslie Scharfenstein; Perng-Kuang Chang
Publication Detail:
Type:  Journal Article     Date:  2010-03-26
Journal Detail:
Title:  Applied and environmental microbiology     Volume:  76     ISSN:  1098-5336     ISO Abbreviation:  Appl. Environ. Microbiol.     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-05-07     Completed Date:  2010-08-10     Revised Date:  2010-11-02    
Medline Journal Info:
Nlm Unique ID:  7605801     Medline TA:  Appl Environ Microbiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3374-7     Citation Subset:  IM    
Affiliation:
Southern Regional Research Center, Agricultural Research Service, USDA, New Orleans, LA 70124, USA. ken.ehrlich@ars.usda.gov
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MeSH Terms
Descriptor/Qualifier:
Aflatoxins / biosynthesis*
Amino Acid Sequence
Anthracenes / chemistry,  metabolism
Aspergillus / enzymology*,  genetics*
Bacterial Proteins / chemistry,  genetics,  metabolism*
Escherichia coli / genetics
Fungi / enzymology,  genetics
Molecular Sequence Data
Multigene Family / genetics
Oxidoreductases / chemistry,  genetics*,  metabolism*
Sequence Alignment
Chemical
Reg. No./Substance:
0/Aflatoxins; 0/Anthracenes; 0/Bacterial Proteins; 0/HypC protein, Bacteria; 90-44-8/anthrone; EC 1.-/Oxidoreductases

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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