| Hygroscopic dilator (Dilapan-S(trade mark)) and misoprostol combination for the early first-trimester termination of pregnancy: a pilot study. | |
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MedLine Citation:
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PMID: 19126319 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND AND METHODOLOGY: Uptake of the mifepristone/misoprostol combination to induce early medical abortion in England and Wales has been slow. Women's concern that early medical abortion is painful may be a contributory factor. This pilot study evaluated the pain experienced by women when Dilapan-S(trade mark), a synthetic hygroscopic dilator (polyacrylonitrile) is used instead of mifepristone as cervical preparation prior to administration of a misoprostol. RESULTS: Of 25 patients completing the trial, 17 aborted in a median of 6 hours with an interquartile range of 4.5-11.5 hours. Of these, 15 patients recorded mild discomfort only, 14 considered the procedure excellent and three good. DISCUSSION AND CONCLUSIONS: This study suggests that the Dilapan-S/misoprostol combination reduces the pain associated with early medical abortion. Further investigation of the protocol is merited. |
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Authors:
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Mannampallil I Samuel; John H Parsons |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The journal of family planning and reproductive health care / Faculty of Family Planning & Reproductive Health Care, Royal College of Obstetricians & Gynaecologists Volume: 35 ISSN: 1471-1893 ISO Abbreviation: J Fam Plann Reprod Health Care Publication Date: 2009 Jan |
Date Detail:
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Created Date: 2009-01-07 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101087687 Medline TA: J Fam Plann Reprod Health Care Country: England |
Other Details:
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Languages: eng Pagination: 45-7 Citation Subset: IM |
Affiliation:
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Department of Sexual Health, King's College Hospital NHS Trust, London, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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