Document Detail


Hydroxyurea induced dermatomyositis-like eruption.
MedLine Citation:
PMID:  22881475     Owner:  NLM     Status:  In-Data-Review    
Abstract/OtherAbstract:
Medication-induced dermatomyositis (DM) is rare, but a recent review highlighted hydroxyurea (HU) as the most common inciting agent. To aid diagnosis, HU-induced DM-like eruption (HU DM-LE) forms a distinct dermopathy where the typical cutaneous features of DM are without systemic involvement and co-exist with other HU-induced cutaneous findings such as severe xerosis, atrophy, stomatitis, cutaneous and mucosal ulceration and melanonychia. On cessation of HU the DM-LE clears avoiding unnecessary immunosuppression and demonstrating the importance of consideration of medication aetiology in DM presentations. We present a case report and review of the literature.
Authors:
Tania M Zappala; Karl Rodins; James Muir
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Publication Detail:
Type:  Journal Article     Date:  2011-05-31
Journal Detail:
Title:  The Australasian journal of dermatology     Volume:  53     ISSN:  1440-0960     ISO Abbreviation:  Australas. J. Dermatol.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-08-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0135232     Medline TA:  Australas J Dermatol     Country:  Australia    
Other Details:
Languages:  eng     Pagination:  e58-60     Citation Subset:  IM    
Copyright Information:
© 2011 The Authors. Australasian Journal of Dermatology © 2011 The Australasian College of Dermatologists.
Affiliation:
Mater Misericordiae Hospital, Department of Dermatology, Brisbane, Queensland, Australia.
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