| Hydroxyproline excretion in schoolchildren and its relationship to measures of indoor air pollution. | |
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MedLine Citation:
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PMID: 3570486 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The urinary hydroxyproline excretion was investigated in a population of 6- to 9-year-old schoolchildren living in the Netherlands. Early morning samples of urine were collected at the end of a week in which personal and home monitoring for nitrogen dioxide (NO2) was carried out, and in which detailed information on gas appliances and on parental smoking habits was gathered. In addition, the pulmonary function of the children was measured, and their respiratory symptoms were collected using a standardized questionnaire which was completed by the parents. The hydroxyproline concentrations were standardized for urinary creatinine content. The hydroxyproline/creatinine ratio (HOP/C ratio) was found to be unrelated to NO2 exposure. The presence of major NO2-sources in the kitchen, vented and unvented gas-fired waterheaters, was significantly associated with elevated HOP/C ratios, due to a negative relationship with the creatinine concentration. There was a tendency for HOP/C to increase with the amount of tobacco smoked in the presence of a child. Respiratory symptoms and pulmonary function were unrelated to HOP/C. In this population, the urinary HOP/C ratio was not found to be a close correlate of exposure to NO2 or tobacco smoke, and of respiratory symptoms and pulmonary function. |
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Authors:
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A J Verplanke; B Remijn; F Hoek; D Houthuijs; B Brunekreef; J S Boleij |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International archives of occupational and environmental health Volume: 59 ISSN: 0340-0131 ISO Abbreviation: Int Arch Occup Environ Health Publication Date: 1987 |
Date Detail:
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Created Date: 1987-06-17 Completed Date: 1987-06-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7512134 Medline TA: Int Arch Occup Environ Health Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 221-31 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Air Pollutants
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analysis Air Pollution* Child Climate* Environmental Exposure Female Housing Humans Hydroxyproline / urine* Lung Volume Measurements Male Microclimate* Netherlands Nitric Oxide / analysis Smoking |
| Chemical | |
Reg. No./Substance:
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0/Air Pollutants; 10102-43-9/Nitric Oxide; 51-35-4/Hydroxyproline |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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