Document Detail


Hydroxycut hepatotoxicity: a case series and review of liver toxicity from herbal weight loss supplements.
MedLine Citation:
PMID:  19058338     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Dietary supplements represent an increasingly common source of drug-induced liver injury. Hydroxycut is a popular weight loss supplement which has previously been linked to hepatotoxicity, although the individual chemical components underlying liver injury remain poorly understood. We report two cases of acute hepatitis in the setting of Hydroxycut exposure and describe possible mechanisms of liver injury. We also comprehensively review and summarize the existing literature on commonly used weight loss supplements, and their individual components which have demonstrated potential for liver toxicity. An increased effort to screen for and educate patients and physicians about supplement-associated hepatotoxicity is warranted.
Authors:
Lily Dara; Jennifer Hewett; Joseph Kartaik Lim
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  World journal of gastroenterology : WJG     Volume:  14     ISSN:  1007-9327     ISO Abbreviation:  World J. Gastroenterol.     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-12-05     Completed Date:  2009-05-19     Revised Date:  2013-06-04    
Medline Journal Info:
Nlm Unique ID:  100883448     Medline TA:  World J Gastroenterol     Country:  China    
Other Details:
Languages:  eng     Pagination:  6999-7004     Citation Subset:  IM    
Affiliation:
Department of Medicine, Griffin Hospital, Derby, CT 06520, USA.
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MeSH Terms
Descriptor/Qualifier:
Acute Disease
Adult
Anti-Obesity Agents / adverse effects*
Dietary Supplements / adverse effects
Drug-Induced Liver Injury / etiology*
Female
Humans
Plant Preparations / adverse effects*
Chemical
Reg. No./Substance:
0/Anti-Obesity Agents; 0/Plant Preparations; 0/hydroxycut
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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