| Hydroxyapatite crystals biologically inspired on titanium by using an organic template based on the copolymer of acrylic acid and itaconic acid. | |
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MedLine Citation:
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PMID: 19165792 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Hydroxyapatite coating on metal implants is an effective method to enhance bioactive properties of the metal surface. We report here a method to coat the Ti-6Al-4V alloy with hydroxyapatite crystals. After alkaline/heat treatment, the spontaneous growth of organoapatite on titanium alloy surface involves sequential preadsorption of titanium isopropoxide (TIPO) and the copolymer of acrylic acid and itaconic acid on the metal, followed by exposure to simulated body fluid (SBF). The organoapatite characterization of the coating was carried out by scanning electron microscopy, energy dispersive spectrometer, and X-ray diffraction. The copolymer of acrylic acid and itaconic acid overlayer which is rich of carboxylate groups can lead to the deposition of needle-like and homogeneous HA on the surface after immersion in SBF. |
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Authors:
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Chao Zhang; Zhi-An Li; Xiang-Rong Cheng; Qun Xiao; Hong-Bo Li |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of biomedical materials research. Part A Volume: 92 ISSN: 1552-4965 ISO Abbreviation: J Biomed Mater Res A Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2009-11-25 Completed Date: 2010-02-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101234237 Medline TA: J Biomed Mater Res A Country: United States |
Other Details:
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Languages: eng Pagination: 63-9 Citation Subset: IM |
Affiliation:
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Key Laboratory of Oral Biomedical Engineering, Ministry of Education, School and Hospital of Stomatology, Wuhan University, Wuhan 430079, People's Republic of China. lizhian2001@yahoo.com.cn |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Body Fluids
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chemistry* Calcium / analysis Chemical Precipitation / drug effects Crystallization Durapatite / pharmacology* Microscopy, Electron, Scanning Phosphorus / analysis Polymers / pharmacology* Solutions Surface Properties / drug effects Titanium / pharmacology* X-Ray Diffraction |
| Chemical | |
Reg. No./Substance:
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0/Polymers; 0/Solutions; 12743-70-3/titanium alloy (TiAl6V4); 1306-06-5/Durapatite; 25948-33-8/itaconic-acrylic acid copolymer; 7440-32-6/Titanium; 7440-70-2/Calcium; 7723-14-0/Phosphorus |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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