| Hydroquinone, a benzene metabolite, and leukemia: A case report and review of the literature. | |
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MedLine Citation:
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PMID: 21511898 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Hydroquinone is a phenolic metabolite of benzene, a known human carcinogen. Hydroquinone is widely used in the industry. We report a case of a 43-year-old male diagnosed with antecedent myelodysplastic syndrome and acute myeloid leukemia following 16 years of occupational exposure to hydroquinone in radiographic developer solution. Cytogenetic studies revealed aberrations in chromosome 5 and chromosome 7. We review the literature on hydroquinone as a potential cause of hematolymphatic cancers and discuss the role of hydroquinone as a genotoxic and leukemogenic agent. |
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Authors:
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Lee Regev; Michael Wu; Ronald Zlotolow; Nachman Brautbar |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-4-21 |
Journal Detail:
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Title: Toxicology and industrial health Volume: - ISSN: 1477-0393 ISO Abbreviation: - Publication Date: 2011 Apr |
Date Detail:
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Created Date: 2011-4-22 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8602702 Medline TA: Toxicol Ind Health Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Nachman Brautbar, M.D., Inc., Los Angeles, CA, USA. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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