Document Detail


Hydrops fetalis secondary to Bart hemoglobinopathy.
MedLine Citation:
PMID:  3945425     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Alpha-thalassemia is the most common cause of hydrops fetalis among Southeast Asians. With the recent influx of Southeast Asian refugees and the rapidly growing Filipino population this will become an increasingly important obstetric problem in the United States. Homozygous alpha-thalassemia, or Bart hemoglobinopathy, is invariably fatal to the fetus and produces significant maternal morbidity. Eighteen cases of homozygous alpha-thalassemia in one hospital are reviewed. This is the largest series reported in the United States. Recommendations are made for antenatal screening, diagnosis, and management of alpha-thalassemia.
Authors:
R Nakayama; D Yamada; V Steinmiller; E Hsia; R W Hale
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  67     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  1986 Feb 
Date Detail:
Created Date:  1986-02-28     Completed Date:  1986-02-28     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  176-80     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Autopsy
Continental Population Groups
Edema / etiology*,  pathology
Female
Fetal Diseases / etiology*,  pathology
Genetic Counseling
Hawaii
Hemoglobins / genetics
Humans
Pregnancy
Prenatal Diagnosis
Thalassemia / congenital*,  epidemiology
Chemical
Reg. No./Substance:
0/Hemoglobins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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