| Hydromorphone effects on human conversational speech. | |
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MedLine Citation:
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PMID: 6083576 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The present study provides an objective assessment of the increased talkativeness associated with acute opiate drug administration. Speech of five methadone-maintenance subjects was recorded continuously for 1 h following the injection of 0, 10, 14, or 18 mg hydromorphone. Dose-related increases in subjects' speech were observed, while no systematic changes were seen in speech of an undrugged partner. Dose-related increases were also obtained on an adjective checklist measuring characteristic opiate signs and symptoms. The relationship between behavioral, subjective, and reinforcing drug effects is discussed. |
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Authors:
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M L Stitzer; M E McCaul; G E Bigleow; I A Liebson |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Psychopharmacology Volume: 84 ISSN: 0033-3158 ISO Abbreviation: Psychopharmacology (Berl.) Publication Date: 1984 |
Date Detail:
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Created Date: 1985-02-14 Completed Date: 1985-02-14 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7608025 Medline TA: Psychopharmacology (Berl) Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 402-4 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Dose-Response Relationship, Drug Humans Hydromorphone / pharmacology* Male Speech / drug effects* Time Factors |
| Grant Support | |
ID/Acronym/Agency:
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DA-01472/DA/NIDA NIH HHS; DA-01943/DA/NIDA NIH HHS; DA-03198/DA/NIDA NIH HHS |
| Chemical | |
Reg. No./Substance:
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466-99-9/Hydromorphone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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