Document Detail


Hydrolysis of Chicoric and Caftaric Acids with Esterases and Lactobacillus johnsonii in Vitro and in a Gastrointestinal Model.
MedLine Citation:
PMID:  22920606     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Chicoric acid (ChA) and caftaric acid (CafA) were identified as bioactive components of chicory and have been ascribed to a number of health benefits. In this study we investigated the hydrolysis of ChA and CafA with enzymes and a probiotic bacterium Lactobacillus johnsonii (La1). Chlorogenate esterase (24 U/mg) hydrolyzed 100% of ChA (10 mM) and CafA (10 mM) after 3 h, at pH 7.0 and 37 °C. Under the same reaction conditions, 100% hydrolysis of ChA and CafA was achieved with a spray-dried preparation of La1. The addition of La1 (100 mg/ml, 3.3 E9 cfu/g) to CafA solution in a gastrointestinal model (GI-model) resulted in 65% hydrolysis of CafA. This model simulates the physico-chemical conditions of human gastro intestinal tract. No hydrolysis of CafA was observed after the passage through the GI-model in the absence of La1. The results of this study support the hypothesis that ChA and CafA are degraded by gut microflora before absorption and metabolization.
Authors:
Rachid Bel-Rhlid; Nicole Pagé-Zoerkler; René Fumeaux; Thang Ho-Dac; Jean-Yves Chuat; Jean-Luc Sauvageat; Thomas Raab
Related Documents :
16507706 - Effects of fatty acid supplements on ruminal and total tract nutrient digestion in lact...
7059566 - The origin of urinary aromatic compounds excreted by ruminants. 1. the metabolism of qu...
3621086 - Inhibition of methanogenesis in pure cultures by ammonia, fatty acids, and heavy metals...
8215896 - Development of rumen metabolism and ruminal epithelium in lambs.
7952006 - Analysis of dansyl amino acids in feedstuffs and skin by micellar electrokinetic capill...
10388516 - The hnf-3alpha transcription factor is a primary target for retinoic acid action.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-26
Journal Detail:
Title:  Journal of agricultural and food chemistry     Volume:  -     ISSN:  1520-5118     ISO Abbreviation:  J. Agric. Food Chem.     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-27     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0374755     Medline TA:  J Agric Food Chem     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Indications and performance of pelvic radiography in patients with blunt trauma.
Next Document:  Antinociceptive interaction of (+/-)-CPP and propentofylline in monoarthritic rats.