Document Detail


Hydrogen sulfide-mediated myocardial pre- and post-conditioning.
MedLine Citation:
PMID:  21373204     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Coronary artery disease is a major cause of morbidity and mortality in the Western world. Acute myocardial infarction, resulting from coronary artery atherosclerosis, is a serious and often fatal consequence of coronary artery disease, resulting in cell death in the myocardium. Pre- and post-conditioning of the myocardium are two treatment strategies that reduce the amount of cell death significantly. Hydrogen sulfide has recently been identified as a potent cardioprotective signaling molecule, which is a highly effective pre- and post-conditioning agent. The cardioprotective signaling pathways involved in hydrogen sulfide-based pre- and post-conditioning will be explored in this article.
Authors:
Benjamin L Predmore; David J Lefer
Related Documents :
19307404 - Caveats in the management and diagnosis of cerebellar infarct and vertebral artery diss...
3738944 - The clinical spectrum of hemorrhagic infarction.
844024 - Recurrent hemorrhage from corpus luteum during anticoagulant therapy.
16684064 - Cardiopulmonary bypass for complex cardiac surgery using bivalirudin anticoagulation in...
3943934 - The effect of infarct size on atrioventricular and intraventricular conduction disturba...
18307844 - Signs and symptoms in diagnosing acute myocardial infarction and acute coronary syndrom...
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Expert review of clinical pharmacology     Volume:  4     ISSN:  1751-2441     ISO Abbreviation:  Expert Rev Clin Pharmacol     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2012-01-04     Completed Date:  2012-09-04     Revised Date:  2014-09-19    
Medline Journal Info:
Nlm Unique ID:  101278296     Medline TA:  Expert Rev Clin Pharmacol     Country:  England    
Other Details:
Languages:  eng     Pagination:  83-96     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Animals
Cardiotonic Agents / metabolism*,  therapeutic use
Coronary Vessels / metabolism
Humans
Hydrogen Sulfide / metabolism*,  therapeutic use
Ischemic Postconditioning* / methods
Ischemic Preconditioning, Myocardial* / methods
Myocardial Reperfusion Injury / drug therapy,  metabolism
Myocardium / metabolism*
Signal Transduction / physiology
Grant Support
ID/Acronym/Agency:
1R01 HL093579-01A1/HL/NHLBI NIH HHS; 5R01 HL092141-02/HL/NHLBI NIH HHS; R01 HL092141/HL/NHLBI NIH HHS; R01 HL092141-04/HL/NHLBI NIH HHS; R01 HL093579/HL/NHLBI NIH HHS; R01 HL093579-03/HL/NHLBI NIH HHS
Chemical
Reg. No./Substance:
0/Cardiotonic Agents; YY9FVM7NSN/Hydrogen Sulfide
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Beyond patient reported pain: perfusion magnetic resonance imaging demonstrates reproducible cerebra...
Next Document:  Violence exposure and health related risk among African American adolescent female detainees: A stra...