| Hydrodynamic focusing-a versatile tool. | |
| | |
MedLine Citation:
|
PMID: 21952728 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
The control of hydrodynamic focusing in a microchannel has inspired new approaches for microfluidic mixing, separations, sensors, cell analysis, and microfabrication. Achieving a flat interface between the focusing and focused fluids is dependent on Reynolds number and device geometry, and many hydrodynamic focusing systems can benefit from this understanding. For applications where a specific cross-sectional shape is desired for the focused flow, advection generated by grooved structures in the channel walls can be used to define the shape of the focused flow. Relative flow rates of the focused flow and focusing streams can be manipulated to control the cross-sectional area of the focused flows. This paper discusses the principles for defining the shape of the interface between the focused and focusing fluids and provides examples from our lab that use hydrodynamic focusing for impedance-based sensors, flow cytometry, and microfabrication to illustrate the breadth of opportunities for introducing new capabilities into microfluidic systems. We evaluate each example for the advantages and limitations integral to utilization of hydrodynamic focusing for that particular application. |
| | |
Authors:
|
Joel P Golden; Gusphyl A Justin; Mansoor Nasir; Frances S Ligler |
Related Documents
:
|
11247388 - Morphological changes and morphological-functional correlations in acute experimental i... 8276038 - Differences in the vascular response to terbutaline in the native and transplanted rat ... 22441618 - Vascular occlusion or not during liver resection: the continuing story. 7460868 - Thoracic duct cannulation via a transjugular vascular endoscope (lymphoscope) in the dog. 9754968 - Regional blood flow in conscious rats after head-down suspension. 8780808 - "small volume resuscitation" as treatment of cerebral blood flow disturbances and incre... |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-9-29 |
Journal Detail:
|
Title: Analytical and bioanalytical chemistry Volume: - ISSN: 1618-2650 ISO Abbreviation: - Publication Date: 2011 Sep |
Date Detail:
|
Created Date: 2011-9-28 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 101134327 Medline TA: Anal Bioanal Chem Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Naval Research Laboratory, Center for Bio/Molecular Science and Engineering, 4555 Overlook Ave SW, Washington, DC, 20375, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Tuning of the morphology of a riboflavin-melamine equimolar supramolecular assembly by in situ silve...
Next Document: The Agrobacterium-mediated transformation of common wheat (Triticum aestivum L.) and triticale (x Tr...