| Hydrodynamic characteristics of porcine aortic valves cross-linked with glutaraldehyde and polyepoxy compounds. | |
| | |
MedLine Citation:
|
PMID: 19092670 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Porcine aortic valve (AoF) tissues cross-linked with glutaraldehyde and epoxy compounds were reported to have high anticalcification properties, but their hydrodynamic characteristics have not been evaluated. The aim of the present study was to investigate the hydrodynamic differences between porcine AoFs, cross-linked with concomitant use of an epoxy compound and glutaraldehyde, at different fixation periods. The valves were mounted on a pulsatile flow circulation mimicking a left heart. The left atrial and left ventricular pressures and mitral and aortic flows were measured at every 0.002 seconds, and the hydrodynamic factor of the valves mounted on the mitral position was estimated. Effective orifice area and the regurgitation volume, which are used as indicators of valve efficiency, failed to detect significant differences due to glutaraldehyde fixation time. In addition, the pressure gradient across the bioprosthetic valve and the variation of mitral flow also had no significant differences. The flow circuit model of the present study was mimicking of a left heart. The evaluation of the mitral valvular function with different glutaraldehyde fixation times was accomplished by relating the pressure with the flow, and by estimating the time lag between valve motion and transvalvular flow. |
| | |
Authors:
|
Aiko Soda; Ryou Tanaka; Yuuto Saida; Kazuaki Takashima; Tomohiro Hirayama; Mitsuo Umezu; Yoshihisa Yamane |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: ASAIO journal (American Society for Artificial Internal Organs : 1992) Volume: 55 ISSN: 1538-943X ISO Abbreviation: ASAIO J. Publication Date: 2009 Jan-Feb |
Date Detail:
|
Created Date: 2009-01-13 Completed Date: 2009-03-19 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9204109 Medline TA: ASAIO J Country: United States |
Other Details:
|
Languages: eng Pagination: 13-8 Citation Subset: IM |
Affiliation:
|
Faculty of Agriculture, Department of Veterinary Surgery, Tokyo University of Agriculture and Technology, Saiwai-cho, Fuchu-shi, Tokyo, Japan. aiko@vet.ne.jp |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Aortic Valve / surgery Bioprosthesis* Cardiovascular Physiological Processes* Cross-Linking Reagents* Epoxy Compounds* Glutaral* Heart Valve Prosthesis* Materials Testing Prosthesis Design Rheology Swine |
| Chemical | |
Reg. No./Substance:
|
0/Cross-Linking Reagents; 0/Epoxy Compounds; 111-30-8/Glutaral |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Microbubble activity in miniaturized and in conventional extracorporeal circulation.
Next Document: Extracorporeal membrane oxygenation circulatory support after congenital cardiac surgery.