| Hydride-based silica stationary phases for HPLC: fundamental properties and applications. | |
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MedLine Citation:
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PMID: 16276778 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Silica hydride is a recent development in chromatographic support materials for HPLC where hydride groups replace 95% of the silanols on the surface. This conversion changes many of the fundamental properties of the material as well as the bonded stationary phases that are the result of further chemical modification of the hydride surface. The general approach for fabricating the silica hydride and subsequent bonded phases is reviewed. Properties of the silica hydride surface are compared to those of the standard material obtained in the preparation of most commercial HPLC stationary phases. Some unique chromatographic properties of hydride-based phases are described as well as some general application areas where these bonded materials may be used in preference to or have advantages not available from typical stationary phases. |
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Authors:
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Joseph J Pesek; Maria T Matyska |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.; Review |
Journal Detail:
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Title: Journal of separation science Volume: 28 ISSN: 1615-9306 ISO Abbreviation: J Sep Sci Publication Date: 2005 Oct |
Date Detail:
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Created Date: 2005-11-09 Completed Date: 2006-06-15 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 101088554 Medline TA: J Sep Sci Country: Germany |
Other Details:
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Languages: eng Pagination: 1845-54 Citation Subset: IM |
Affiliation:
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Department of Chemistry, San Jose State University, CA, USA. pesek@sjsu.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Chromatography, High Pressure Liquid* Silicates* Silicon Dioxide* |
| Grant Support | |
ID/Acronym/Agency:
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0819210-21//PHS HHS; GM 0063519-01/GM/NIGMS NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Silicates; 0/silica hydride; 7631-86-9/Silicon Dioxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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