Document Detail


Hydraulic regulation of brain parenchymal volume.
MedLine Citation:
PMID:  1687334     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A mechanism for the hydraulic regulation of brain parenchymal volume is hypothesized. Ventricular fluid pressure is transmitted to parenchymal capillaries and affects the pressure difference across the capillary wall, thereby influencing the rate of movement of fluid from the capillary lumen to interstitial fluid. The tendency for brain parenchyma to expand results from the resistance encountered by interstitial fluid as it slowly passes through the complex interstices of extracellular space. The tendency for the brain parenchyma to become smaller results, not from compression of tissue by ventricular fluid, but from an inherent elasticity of brain tissue. The parenchymal volume is stable only when the opposing tendencies are balanced. The critical site of action for the hydraulic control of parenchymal volume is the capillary wall, and the fundamental relationship governing this can be expressed mathematically.
Authors:
K R Winston; R E Breeze
Related Documents :
7654964 - Transfer function comparisons of rat aortic wall image and intravascular pressure harmo...
1813704 - The colloid-crystalloid controversy.
16352954 - Induction of hypothermia in patients with various types of neurologic injury with use o...
12970954 - Relative safety of traditional agricultural tractor power take-off (pto) drivelines com...
1273994 - Responses of the cardiovascular system to carotid sinus nerve stimulation.
14525804 - Randomized short-term trial of two autocpap devices versus fixed continuous positive ai...
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Neurological research     Volume:  13     ISSN:  0161-6412     ISO Abbreviation:  Neurol. Res.     Publication Date:  1991 Dec 
Date Detail:
Created Date:  1992-05-22     Completed Date:  1992-05-22     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  7905298     Medline TA:  Neurol Res     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  237-47     Citation Subset:  IM    
Affiliation:
Department of Surgery (Neurosurgery), University of Colorado, Denver.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:
Body Water / metabolism
Cerebral Ventricles
Humans
Hydrocephalus / pathology,  physiopathology*
Intracranial Pressure / physiology*
Pseudotumor Cerebri / pathology*
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Measurement of canine cerebral oedema using vector impedance methods.
Next Document:  Transcranial Doppler ultrasound in brain death: experience in 140 patients.