Document Detail


Hydrated sodium calcium aluminosilicate: a high affinity sorbent for aflatoxin.
MedLine Citation:
PMID:  2837754     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Aluminas, silicas and aluminosilicates were evaluated for their ability to sorb radiolabeled aflatoxin B1 (AFB1) from aqueous solution (in vitro). Hydrated sodium calcium aluminosilicate (HSCAS) was selected for testing in vivo due to its high affinity for AFB1, because of its stable association with AFB1, and its GRAS (generally recognized as safe) status as an anticaking agent. The HSCAS, when added to the diet of Leghorn and broiler chicks at a level of .5%, significantly diminished the adverse effects of feeding 7.5 mg AFB1/kg of feed. Thus, this agent (and other aluminosilicate congeners) may prove effective in the preventive management of aflatoxicosis.
Authors:
T D Phillips; L F Kubena; R B Harvey; D R Taylor; N D Heidelbaugh
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Poultry science     Volume:  67     ISSN:  0032-5791     ISO Abbreviation:  Poult. Sci.     Publication Date:  1988 Feb 
Date Detail:
Created Date:  1988-07-27     Completed Date:  1988-07-27     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  0401150     Medline TA:  Poult Sci     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  243-7     Citation Subset:  IM    
Affiliation:
Department of Veterinary Public Health, College of Veterinary Medicine, Texas A&M University, College Station 77843.
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MeSH Terms
Descriptor/Qualifier:
Absorption
Adsorption
Aflatoxin B1
Aflatoxins* / poisoning
Aluminum Hydroxide
Aluminum Silicates*
Animals
Chickens
Male
Poultry Diseases / chemically induced,  prevention & control
Zeolites
Chemical
Reg. No./Substance:
0/Aflatoxins; 0/Aluminum Silicates; 1162-65-8/Aflatoxin B1; 1318-02-1/Zeolites; 21645-51-2/Aluminum Hydroxide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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