Document Detail


Hybridization and reaction-based fluorogenic nucleic acid probes.
MedLine Citation:
PMID:  22911172     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We developed fluorogenic probes, which are photoactivated in the presence of specific nucleic acid templates with the release of fluorescent dyes. This templated reaction can be used to target specific nucleic acids in complex mixtures. We further demonstrate that this reaction can be monitored by single-molecule fluorescence imaging.
Authors:
Subrata Dutta; Benjamin Flottmann; Mike Heilemann; Andriy Mokhir
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-22
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  -     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Anorganisch-Chemisches Institut, Ruprecht-Karls-Universität Heidelberg, INF 270, Heidelberg, Germany. Andriy.Mokhir@urz.uni-heidelberg.de.
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