Document Detail

Hybrid palliation for neonates with hypoplastic left heart syndrome: current strategies and outcomes.
MedLine Citation:
PMID:  20339493     Owner:  NLM     Status:  PubMed-not-MEDLINE    
In the last decade the hybrid procedure has emerged as an alternative stage I palliation in neonates with hypoplastic left heart syndrome (HLHS). This review discusses the historical aspect, surgical and interventional techniques, current outcomes and future direction of this procedure. Hybrid palliation yields equivalent but not superior stage I palliation survival and comparable 1-year survival to conventional Norwood palliation, comparable prestage II hemodynamics and pulmonary artery growth, and preserved ventricular function in stage II palliation. Hybrid palliation utilizes significantly less resource and shortens postoperative recovery. In comprehensive stage II palliation the impact of pulmonary artery reconstruction on subsequent pulmonary artery growth has not been determined and should be further investigated. A prospective, randomized trial is warranted to compare these two surgical strategies for neonates with hypoplastic left heart syndrome.
Osami Honjo; Christopher A Caldarone
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Publication Detail:
Type:  Journal Article     Date:  2010-03-24
Journal Detail:
Title:  Korean circulation journal     Volume:  40     ISSN:  1738-5555     ISO Abbreviation:  Korean Circ J     Publication Date:  2010 Mar 
Date Detail:
Created Date:  2010-03-26     Completed Date:  2011-07-14     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101247141     Medline TA:  Korean Circ J     Country:  Korea (South)    
Other Details:
Languages:  eng     Pagination:  103-11     Citation Subset:  -    
Division of Cardiovascular Surgery, Hospital for Sick Children, Toronto, Ontario, Canada.
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