| Hybrid Ablation using Percutaneous and Endoscopic Approach for Multi-Nodular Hepatocellular Carcinomas. | |
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MedLine Citation:
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PMID: 22469728 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Background/Aims: To investigate the efficacy and the safety of a hybrid ablation combining a percutaneous and endoscopic approach for multi-nodular hepatocellular carcinomas. Methodology: Hybrid ablation consists of a percutaneous approach for deep-sited tumors and an endoscopic approach for superficial ones. Between January 1991 and December 2007, fortyeight patients with 139 nodules were treated with hybrid ablation. The perioperative clinical data and prognosis of the hybrid approach group were compared with 15 patients with superficial and deep-sited multinodular HCCs treated by the pure endoscopic ablation. Results: With regard to the deep-site of the liver tumors, the complete disappearance of tumor enhancement was observed in 76 of 77 tumors (98.7%) in the hybrid ablation group and 15 of 18 tumors (83.3%) in the pure endoscopic ablation group (p=0.02). The mean operation time (236.5min), the mean amount of intraoperative bleeding (20.3g), the median days of postoperative hospital stay (14 days), major complication rates (10.4%) and the 5-year overall survival (42%) in the hybrid ablation group were similar to the pure endoscopic group. Conclusions: Hybrid ablation is a clinically useful treatment for multi-nodular hepatocellular carcinomas located in both the superficial and deep-site of the liver. |
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Authors:
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Toshiro Masuda; Toru Beppu; Takao Mizumoto; Takatoshi Ishiko; Akira Chikamoto; Hiromitsu Hayashi; Hirohisa Okabe; Ryu Otao; Hasita Horlad; Hiroshi Takamori; Hideo Baba |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Hepato-gastroenterology Volume: 59 ISSN: 0172-6390 ISO Abbreviation: Hepatogastroenterology Publication Date: 2012 May-Jun |
Date Detail:
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Created Date: 2012-04-03 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8007849 Medline TA: Hepatogastroenterology Country: Greece |
Other Details:
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Languages: eng Pagination: 836-9 Citation Subset: IM |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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