Document Detail

Hyaluronate-iodine complex: a new adjunct for the management of complex sternal wounds after a cardiac operation.
MedLine Citation:
PMID:  22106326     Owner:  NLM     Status:  In-Data-Review    
A wound-healing agent developed in the European Union is based on the combination of organic hyaluronan with inorganic iodine. The aim of this pilot study was to assess the efficacy and safety of hyaluronate-iodine in the treatment of sternal wounds. Eight patients with sternal wound dehiscence were entered into the study. After debridement, wounds were dressed with gauze soaked in hyaluronate-iodine. In one patient with an epipleural abscess, hyaluronate-iodine was instilled directly into the abscess cavity daily. Complete healing was achieved in 7 patients, and 1 patient underwent a reconstructive operation for wound closure. The mean (SD) length of treatment was 136 (114.2) days. No adverse effects or complications were apparent in this group. Hyaluronate-iodine is safe and effective in healing sternal wound dehiscence. Randomized controlled trials are needed for further validation.
Robert A Brenes; Lubos Sobotka; Michael S Ajemian; Jan Manak; Pavel Vyroubal; Miroslava Slemrova; Vladimira Adamkova; Jiri Zajic; Stanley J Dudrick
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of surgery (Chicago, Ill. : 1960)     Volume:  146     ISSN:  1538-3644     ISO Abbreviation:  Arch Surg     Publication Date:  2011 Nov 
Date Detail:
Created Date:  2011-11-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9716528     Medline TA:  Arch Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1323-5     Citation Subset:  AIM; IM    
The Stanley J. Dudrick Department of Surgery, St Mary's Hospital, 56 Franklin St, Waterbury, CT 06706.
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