Document Detail


Hyalinizing clear cell carcinoma of the head and neck: Case series and update.
MedLine Citation:
PMID:  25352039     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Background: Hyalinizing clear cell carcinoma (HCCC) is a rare neoplasm of salivary gland origin which is low-grade in nature. In this series we report on 9 cases of HCCC and update the literature. Methods: A comprehensive literature search was performed. Our institutional database was queried for cases of HCCC. Pathology reports and slides were reviewed. Data was extracted including demographics, staging, primary treatment, histopathologic findings, recurrence and disease status. Statistical analysis was performed using a Pearson's chi-squared test. Results: 136 total cases were included for analysis. The overall recurrence rate was 19.8%. Necrosis was associated with risk of recurrence (p=0.003). Positive margins and lymph node status were associated with risk of recurrence. Prognosis was good with only 3/82 patients reported dying with disease. Conclusion: HCCC has an overall good prognosis with potential for aggressive behavior. The presence of necrosis, locoregional disease or positive margins is associated with risk for recurrence. Head Neck, 2014.
Authors:
W Greer Albergotti; Elizabeth A Bilodeau; J Kenneth Byrd; Mark M Mims; Stella Lee; Seungwon Kim
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2014-10-28
Journal Detail:
Title:  Head & neck     Volume:  -     ISSN:  1097-0347     ISO Abbreviation:  Head Neck     Publication Date:  2014 Oct 
Date Detail:
Created Date:  2014-10-29     Completed Date:  -     Revised Date:  2014-10-30    
Medline Journal Info:
Nlm Unique ID:  8902541     Medline TA:  Head Neck     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2014 Wiley Periodicals, Inc., A Wiley Company.
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