Document Detail

Hyaline vascular-type Castleman's disease in the hilum of liver: a case report.
MedLine Citation:
PMID:  20193070     Owner:  NLM     Status:  PubMed-not-MEDLINE    
BACKGROUND: Castleman's disease or angiofollicular lymphoid hyperplasia is a rare benign lymph node hyperplasia usually presenting as an asymptomatic mediastinal mass in children. The disease can present at any extra thoracic site with lymphoid tissue such as retroperitoneal, mesentery, axilla, and pelvis. Hepatic localization castleman disease is very rare in children. Herein, we reported a case of Castleman's disease arising from the lymph node in hilum of liver. CASE PRESENTATION: A 5 -year-old girl with chief complaint of abdominal pain for two months which exaggerated in last three days was referred to the hospital. On routine physical examination, only a generalized abdominal pain was noticed. Routine laboratory investigations and Chest X-Ray were normal. Abdominal Sonography revealed a 3.7 x 3.1 cm solid mass in the hilum of the liver. On the MRI images, a lobulated mass in the portal hepatic associated with mass effect on the portal vein was visible. Histological examination revealed expansion of mantle zone in lymphatic nodules accompanied by burnt out germinal centers. This pattern was matched with the diagnosis of the hyaline-vascular type of Castleman disease. The patient underwent a laparotomy. The patient had an uneventful postoperative course. CONCLUSION: This pattern was matched with the diagnosis of the hyaline-vascular type of Castleman disease.
Hossein Karami; Alireza Alam Sahebpour; Maryam Ghasemi; Hasan Karami; Mojdeh Dabirian; Kurosh Vahidshahi; Farzad Masiha; Soheila Shahmohammadi
Publication Detail:
Type:  Journal Article     Date:  2010-03-01
Journal Detail:
Title:  Cases journal     Volume:  3     ISSN:  1757-1626     ISO Abbreviation:  Cases J     Publication Date:  2010  
Date Detail:
Created Date:  2010-03-25     Completed Date:  2010-07-14     Revised Date:  2010-09-30    
Medline Journal Info:
Nlm Unique ID:  101474272     Medline TA:  Cases J     Country:  England    
Other Details:
Languages:  eng     Pagination:  74     Citation Subset:  -    
Department of Pediatric Oncology & Hematology, Thalassemia Research Center, Mazandaran University of Medical Sciences, Booali Sina Hospital, Pasdaran Boulevard, Sari, Po Box: 48158-38477, Iran.
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