Document Detail


Humoral immune response of patients bitten by the snake Bothrops erythromelas.
MedLine Citation:
PMID:  21181034     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
INTRODUCTION: Snake envenomings are a health problem in rural areas of tropical and subtropical countries, but little is known regarding the immune response presented by bitten individuals. The IgM production of patients bitten by Bothrops erythromelas snake was analyzed to identify the effectiveness of treatment in this type of envenomation.
METHODS: Bothrops erythromelas venom was submitted to electrophoresis and transferred to a nitrocellulose sheet, following incubation with patients' sera.
RESULTS: A 38 KDa protein was detected before and 24 h after therapy.
CONCLUSIONS: The result suggests that this protein could be used as a marker for individuals envenomed by Bothrops. erythromelas.
Authors:
Karla Patricia Oliveira Luna; Edeneide Maria Xavier; Vanessa Peruhype Magalhães Pascoal; Olindo Assis Martins-Filho; Valéria Rêgo Alves Pereira
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Revista da Sociedade Brasileira de Medicina Tropical     Volume:  43     ISSN:  1678-9849     ISO Abbreviation:  Rev. Soc. Bras. Med. Trop.     Publication Date:    2010 Nov-Dec
Date Detail:
Created Date:  2010-12-24     Completed Date:  2011-09-29     Revised Date:  2011-10-04    
Medline Journal Info:
Nlm Unique ID:  7507456     Medline TA:  Rev Soc Bras Med Trop     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  731-2     Citation Subset:  IM    
Affiliation:
Departament of Biology, Center of Biological and Health Sciences, State University of Paraíba, Campina Grande, PB, Brazil. karlaceatox@yahoo.com.br
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MeSH Terms
Descriptor/Qualifier:
Animals
Antivenins / administration & dosage,  immunology*
Blotting, Western
Bothrops*
Crotalid Venoms / immunology*
Humans
Immunity, Humoral / immunology*
Immunoglobulin M / biosynthesis*
Snake Bites / drug therapy,  immunology*
Time Factors
Chemical
Reg. No./Substance:
0/Antivenins; 0/Crotalid Venoms; 0/Immunoglobulin M

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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