Document Detail


Humans put their eggs in more than one basket.
MedLine Citation:
PMID:  23263370     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Primordial germ cell (PGC) development in the human fetus remains relatively uncharted. A new study suggests that epigenetic reprogramming and sex differentiation in human PGCs occur asynchronously over an extended time period. This finding raises questions and implications for in vitro PGC differentiation.
Authors:
Diana J Laird
Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Nature cell biology     Volume:  15     ISSN:  1476-4679     ISO Abbreviation:  Nat. Cell Biol.     Publication Date:  2013 Jan 
Date Detail:
Created Date:  2012-12-24     Completed Date:  2013-02-21     Revised Date:  2014-01-23    
Medline Journal Info:
Nlm Unique ID:  100890575     Medline TA:  Nat Cell Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  13-5     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Cell Differentiation*
Female
Genomic Imprinting*
Germ Cells / metabolism*,  physiology*
Humans
Male
Proto-Oncogene Proteins c-kit / metabolism*
Grant Support
ID/Acronym/Agency:
DP2 OD007420/OD/NIH HHS
Chemical
Reg. No./Substance:
EC 2.7.10.1/Proto-Oncogene Proteins c-kit
Comments/Corrections
Comment On:
Nat Cell Biol. 2013 Jan;15(1):113-22   [PMID:  23242216 ]
Erratum In:
Nat Cell Biol. 2013 Feb;15(2):229

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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