| Human tuberculosis--an ancient disease, as elucidated by ancient microbial biomolecules. | |
| | |
MedLine Citation:
|
PMID: 19720155 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Tuberculosis is a major cause of death but infected people with effective immunity may remain healthy for years, suggesting long-term co-existence of host and pathogen. Direct detection and characterisation of ancient microbial DNA and lipid biomarkers confirms palaeopathological diagnoses. Archaeological Mycobacterium tuberculosis resembles extant lineages indicating the timescale for evolutionary changes is considerably longer than originally believed. |
| | |
Authors:
|
Helen D Donoghue |
Related Documents
:
|
20231995 - Increasing pathomorphism of pulmonary tuberculosis: an observational study of slow clin... 16822685 - Cutaneous tuberculosis in morocco. 1907885 - Association of hematuria and mycobacterial infection. 16718935 - Isolated tuberculosis of the vastus lateralis muscle: a case report. 8876265 - Glutathione s-transferase-m1 'null' genotype and alcohol-induced disorders of human spe... 2915965 - The dizzy patient. a practical approach to management. |
Publication Detail:
|
Type: Historical Article; Journal Article; Review Date: 2009-08-29 |
Journal Detail:
|
Title: Microbes and infection / Institut Pasteur Volume: 11 ISSN: 1769-714X ISO Abbreviation: Microbes Infect. Publication Date: 2009 Dec |
Date Detail:
|
Created Date: 2009-11-30 Completed Date: 2010-02-08 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 100883508 Medline TA: Microbes Infect Country: France |
Other Details:
|
Languages: eng Pagination: 1156-62 Citation Subset: IM |
Affiliation:
|
Division of Infection and Immunity, Centre for Infectious Diseases and International Health, University College London, London W1T 4JF, UK. h.donoghue@ucl.ac.uk |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
DNA, Bacterial
/
analysis*,
genetics History, Ancient Humans Mycobacterium tuberculosis / genetics* Paleopathology* Tuberculosis / epidemiology, history*, microbiology |
| Chemical | |
Reg. No./Substance:
|
0/DNA, Bacterial |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Characterization of photoreceptor cell types in the little brown bat Myotis lucifugus (Vespertilioni...
Next Document: Drug transporter, P-glycoprotein (MDR1), is an integrated component of the mammalian blood-testis ba...