Document Detail

Human rhinovirus 14 infection of HeLa cells results in the proteolytic cleavage of the p220 cap-binding complex subunit and inactivates globin mRNA translation in vitro.
MedLine Citation:
PMID:  2985827     Owner:  NLM     Status:  MEDLINE    
One of the characteristics of picornavirus infection of cells in tissue culture is a specific inhibition of utilization of host cell mRNA for protein synthesis. In this study we show that human rhinovirus 14 is similar to poliovirus in that the inhibition of host cell translation that occurs during infection correlates with the proteolytic cleavage of an Mr 220,000 subunit of the cap-binding protein complex.
D Etchison; S Fout
Related Documents :
9787477 - Ultrastructure of the murine cervix following infection with chlamydia trachomatis.
19793537 - The infection of primary avian tracheal epithelial cells with infectious bronchitis virus.
19659427 - Loops and networks in control of francisella tularensis virulence.
18191547 - In vitro effects of suramin on trypanosoma cruzi.
6796747 - Prostaglandin and thromboxane synthesis by rat glomerular epithelial cells.
7961117 - Immunohistochemical demonstration of intestinal-type alkaline phosphatase in stomach tu...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of virology     Volume:  54     ISSN:  0022-538X     ISO Abbreviation:  J. Virol.     Publication Date:  1985 May 
Date Detail:
Created Date:  1985-05-29     Completed Date:  1985-05-29     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  0113724     Medline TA:  J Virol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  634-8     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Carrier Proteins / metabolism*
Globins / biosynthesis*
Hela Cells / microbiology
Molecular Weight
Peptide Initiation Factors / isolation & purification
Protein Biosynthesis*
RNA Cap-Binding Proteins
Rhinovirus / genetics,  metabolism*
Grant Support
Reg. No./Substance:
0/Carrier Proteins; 0/Peptide Initiation Factors; 0/RNA Cap-Binding Proteins; 9004-22-2/Globins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  A candidate for a new serotype of human rotavirus.
Next Document:  Fine mapping and sequencing of a variable segment in the inverted repeat region of varicella-zoster ...