Document Detail


Human proviral mRNAs down regulated in choriocarcinoma encode a zinc finger protein related to Krüppel.
MedLine Citation:
PMID:  2115127     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
RNA transcripts of the HERV-R (ERV3) human provirus that are abundant in placenta but absent in choriocarcinoma contain nonproviral genomic sequences at their 3' ends. We report here the isolation of cDNA clones of these genomic sequences. The transcripts encode a Krüppel-related zinc finger protein consisting of a unique leader region and more than 12 28-amino-acid finger motifs.
Authors:
N Kato; K Shimotohno; D VanLeeuwen; M Cohen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Molecular and cellular biology     Volume:  10     ISSN:  0270-7306     ISO Abbreviation:  Mol. Cell. Biol.     Publication Date:  1990 Aug 
Date Detail:
Created Date:  1990-08-22     Completed Date:  1990-08-22     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  8109087     Medline TA:  Mol Cell Biol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  4401-5     Citation Subset:  IM    
Affiliation:
Virology Division, National Cancer Center Research Institute, Tokyo, Japan.
Data Bank Information
Bank Name/Acc. No.:
GENBANK/M55422
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MeSH Terms
Descriptor/Qualifier:
Amino Acid Sequence
Animals
Base Sequence
Cells, Cultured
Choriocarcinoma / genetics*
Cloning, Molecular
DNA / genetics,  isolation & purification
DNA-Binding Proteins / genetics*
Female
Gene Expression Regulation
Humans
Information Systems
Metalloproteins / genetics*
Mice
Molecular Sequence Data
Multigene Family*
Nucleic Acid Hybridization
Pan troglodytes
Placenta / metabolism
Pregnancy
Proviruses / genetics*
RNA, Messenger / genetics*
Retroviridae / genetics
Transcription, Genetic
Uterine Neoplasms / genetics*
Zinc / metabolism
Chemical
Reg. No./Substance:
0/DNA-Binding Proteins; 0/Metalloproteins; 0/RNA, Messenger; 7440-66-6/Zinc; 9007-49-2/DNA
Comments/Corrections

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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