Document Detail

Human parvovirus B19: immunity of Greek females and prenatal investigation of hydrops fetalis.
MedLine Citation:
PMID:  9306109     Owner:  NLM     Status:  MEDLINE    
Sera from 308 healthy Greek females of reproductive age were examined for specific IgG antibodies to human parvovirus B19 by recombinant-Elisa to determine the immunity rates of this part of population to parvovirus B19. Also paired maternal sera and amniotic fluids from nine pregnancies with hydrops fetalis were investigated for specific IgG and IgM antibodies and parvovirus DNA by polymerase chain reaction and southern hybridization analysis. The latter study was conducted to find out the participation of parvovirus B19 infection in hydrops fetalis cases in Greece. The overall prevalence of IgG antibodies in healthy Greek females was at a rate of 57.8% rising with age. One case of hydrops fetalis out of the nine examined, was diagnosed prenatally as parvovirus B19 maternal-fetal infection. It was a twin pregnancy with one fetus hydropic and the other growth retarded. Premature birth of liveborn infants was followed by neonatal death, 48 h after delivery. The contribution of parvovirus B19 in cases of non-immune hydrops fetalis was at 11% in this part of the world.
V Kyriazopoulou; M Simitsopoulou; J Bondis; E Diza; A Athanasiadis; F Frantzidou; E Souliou
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of obstetrics, gynecology, and reproductive biology     Volume:  74     ISSN:  0301-2115     ISO Abbreviation:  Eur. J. Obstet. Gynecol. Reprod. Biol.     Publication Date:  1997 Aug 
Date Detail:
Created Date:  1998-01-07     Completed Date:  1998-01-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0375672     Medline TA:  Eur J Obstet Gynecol Reprod Biol     Country:  IRELAND    
Other Details:
Languages:  eng     Pagination:  157-60     Citation Subset:  IM    
Aristotelian University of Thessaloniki, School of Medicine, Laboratory of Microbiology, Greece.
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MeSH Terms
Amniotic Fluid / virology
Antibodies, Viral / blood*
Base Sequence
Blotting, Southern
DNA Primers / chemistry
DNA, Viral / analysis,  genetics
Enzyme-Linked Immunosorbent Assay
Erythema Infectiosum / complications*,  immunology,  virology
Hydrops Fetalis / blood,  immunology,  virology*
Immunoglobulin G / blood,  immunology
Immunoglobulin M / analysis,  blood
Parvovirus B19, Human / genetics,  immunology*
Polymerase Chain Reaction
Prenatal Diagnosis / methods*
Reg. No./Substance:
0/Antibodies, Viral; 0/DNA Primers; 0/DNA, Viral; 0/Immunoglobulin G; 0/Immunoglobulin M

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