| Human papillomavirus typing in reporting of condyloma. | |
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MedLine Citation:
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PMID: 23324975 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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BACKGROUND: Monitoring of condylomas is an early evidence of population effectiveness of human papillomavirus (HPV) vaccination programs. If reporting could include HPV typing, the contribution by vaccine HPV types to condyloma burden could be monitored. METHODS: A sentinel site for reporting of condyloma including HPV typing was established at the Centre for Sexual Health in Malmö, Sweden. In 2006 to 2009, when there were few HPV vaccines, 621 subjects with condyloma were reported and HPV genotyped. RESULTS: Ninety-four percent of the condylomas contained genital HPV types. Thirty-five different genital HPV types were identified, with HPV6 (62%), HPV16 (13%), and HPV11 (10%) being the most common. At least 1 of the 4 HPV types in the HPV6/11/16/18 vaccine was detected in 77%. High-risk HPV types were more common in females (45%) than among males (27%) (odds ratio, 1.9; confidence interval, 1.3-2.8). Extended testing among subjects initially negative for HPV found 21 patients with cutaneous types of HPV, including a novel type (HPV153). CONCLUSIONS: This report provides a baseline distribution of HPV types in condylomas before the introduction of an HPV vaccination program in this population. Human papillomavirus typing is feasible in routine condyloma reporting. |
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Authors:
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Erik Sturegård; Hanna Johansson; Johanna Ekström; Bengt-Göran Hansson; Annika Johnsson; Eva Gustafsson; Joakim Dillner; Ola Forslund |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Sexually transmitted diseases Volume: 40 ISSN: 1537-4521 ISO Abbreviation: Sex Transm Dis Publication Date: 2013 Feb |
Date Detail:
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Created Date: 2013-01-17 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 7705941 Medline TA: Sex Transm Dis Country: United States |
Other Details:
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Languages: eng Pagination: 123-9 Citation Subset: IM |
Affiliation:
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From the *WHO HPV LabNet Global Reference Laboratory, Department of Clinical Microbiology, University and Regional Laboratories Region Skåne, Malmö, Sweden; †Department of Medical Microbiology, Lund University, Malmö, Sweden; ‡Centre for Sexual Health, Skåne University Hospital, Sweden; §Regional Centre for Infectious Disease Prevention, Malmö, Sweden; and ¶Departments of Laboratory Medicine, Medical Epidemiology, and Biostatistics, Karolinska Institute and Hospital, Stockholm, Sweden. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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