Document Detail

Human papillomavirus typing in reporting of condyloma.
MedLine Citation:
PMID:  23324975     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Monitoring of condylomas is an early evidence of population effectiveness of human papillomavirus (HPV) vaccination programs. If reporting could include HPV typing, the contribution by vaccine HPV types to condyloma burden could be monitored.
METHODS: A sentinel site for reporting of condyloma including HPV typing was established at the Centre for Sexual Health in Malmö, Sweden. In 2006 to 2009, when there were few HPV vaccines, 621 subjects with condyloma were reported and HPV genotyped.
RESULTS: Ninety-four percent of the condylomas contained genital HPV types. Thirty-five different genital HPV types were identified, with HPV6 (62%), HPV16 (13%), and HPV11 (10%) being the most common. At least 1 of the 4 HPV types in the HPV6/11/16/18 vaccine was detected in 77%. High-risk HPV types were more common in females (45%) than among males (27%) (odds ratio, 1.9; confidence interval, 1.3-2.8). Extended testing among subjects initially negative for HPV found 21 patients with cutaneous types of HPV, including a novel type (HPV153).
CONCLUSIONS: This report provides a baseline distribution of HPV types in condylomas before the introduction of an HPV vaccination program in this population. Human papillomavirus typing is feasible in routine condyloma reporting.
Erik Sturegård; Hanna Johansson; Johanna Ekström; Bengt-Göran Hansson; Annika Johnsson; Eva Gustafsson; Joakim Dillner; Ola Forslund
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Sexually transmitted diseases     Volume:  40     ISSN:  1537-4521     ISO Abbreviation:  Sex Transm Dis     Publication Date:  2013 Feb 
Date Detail:
Created Date:  2013-01-17     Completed Date:  2013-07-09     Revised Date:  2013-10-23    
Medline Journal Info:
Nlm Unique ID:  7705941     Medline TA:  Sex Transm Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  123-9     Citation Subset:  IM    
WHO HPV LabNet Global Reference Laboratory, Department of Clinical Microbiology, University and Regional Laboratories Region Skåne, Malmö, Sweden.
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MeSH Terms
Alphapapillomavirus* / immunology,  isolation & purification
Condylomata Acuminata / epidemiology,  prevention & control*
Genotyping Techniques
Human papillomavirus 11
Human papillomavirus 16
Human papillomavirus 18
Human papillomavirus 6
Middle Aged
Papillomavirus Infections / epidemiology,  prevention & control*
Papillomavirus Vaccines*
Pilot Projects
Population Surveillance*
Public Health
Sweden / epidemiology
Uterine Cervical Neoplasms / epidemiology,  prevention & control*
Young Adult
Reg. No./Substance:
0/Papillomavirus Vaccines
Erratum In:
Sex Transm Dis. 2013 Sep;40(9):760

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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