| Human papillomavirus type 6 associated Buschke-Loewenstein tumor (giant condyloma acuminatum). | |
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MedLine Citation:
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PMID: 8120240 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The term "Buschke-Loewenstein tumor" has been used for tumors with exophytic, wart-like excrescences in the anogenital region. This broadly includes giant condyloma acuminatum and verrucous carcinoma. We report a 44-year-old Japanese man with a giant condyloma acuminatum Buschke-Loewenstein tumor on the right femoinguinal area. The lesion was a huge grape-like nodule composed of multiple small nodules, reaching 135 x 65 x 40 mm in size. Histologically, it showed a regularly acanthotic papilloma with numerous koilocytes in the upper squamous and granular layers. Ultrastructural findings included gradual differentiation from basal cell layers to uppermost corneocytes without disorganized relationships in the epithelial-stromal junction or cellular atypia. Human papillomavirus type 6 DNA was detected in the tumor tissues by polymerase chain reaction and restriction enzyme analysis, although immunohistochemical staining for papillomavirus common antigen was negative. |
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Authors:
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N Kato; H Ueno; H Tanaka; T Nishikawa |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: The Journal of dermatology Volume: 20 ISSN: 0385-2407 ISO Abbreviation: J. Dermatol. Publication Date: 1993 Dec |
Date Detail:
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Created Date: 1994-04-07 Completed Date: 1994-04-07 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7600545 Medline TA: J Dermatol Country: JAPAN |
Other Details:
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Languages: eng Pagination: 773-8 Citation Subset: IM |
Affiliation:
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Department of Dermatology, Otaru City General Hospital, Japan. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Condylomata Acuminata / microbiology*, pathology DNA, Viral / analysis Genital Diseases, Male / microbiology*, pathology Humans Male Papillomaviridae / isolation & purification* Papillomavirus Infections / pathology Tumor Virus Infections / pathology |
| Chemical | |
Reg. No./Substance:
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0/DNA, Viral |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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