Document Detail


Human papillomavirus infection: a concise review of natural history.
MedLine Citation:
PMID:  19546771     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Persistent infection with oncogenic human papillomavirus (HPV), leading to precancerous lesions and potentially cervical cancer, is a serious health burden. The natural history of infection is one that enables the virus to remain immunoevasive within the cervical epithelium and persist for decades. Many studies have provided important information on why some women clear infection and why others do not. The infectious process of HPV may be affected by many cofactors, adding to the complexity of disease development. Vaccination against oncogenic HPV along with cervical screening are two methods that have been developed to provide protection and eliminate the overall burden of disease in women. This article highlights the natural history of oncogenic HPV infection of the cervix and the limitations that currently exist on the literature.
Authors:
Warner K Huh
Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Obstetrics and gynecology     Volume:  114     ISSN:  0029-7844     ISO Abbreviation:  Obstet Gynecol     Publication Date:  2009 Jul 
Date Detail:
Created Date:  2009-06-23     Completed Date:  2009-08-20     Revised Date:  2009-10-26    
Medline Journal Info:
Nlm Unique ID:  0401101     Medline TA:  Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  139-43     Citation Subset:  AIM; IM    
Affiliation:
Department of Obstetrics and Gynecology, University of Alabama Birmingham, Birmingham, Alabama, USA. Warner.Huh@ccc.uab.edu
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Female
Humans
Middle Aged
Papillomavirus Infections* / complications,  virology
Uterine Cervical Neoplasms / etiology
Young Adult

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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