Document Detail


Human papilloma virus 5-DNA in a carcinoma of an epidermodysplasia verruciformis patient infected with various human papillomavirus types.
MedLine Citation:
PMID:  6297727     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
An epidermodysplasia verruciformis patient suffering from generalized warts and a carcinoma at the forehead was found to be infected by at least six types and subtypes of human papillomaviruses. The central part of the carcinoma, however, harbored only human papillomavirus 5 DNA. The DNA persisted extrachromosomally in high genome copy number. In contrast to wart DNA preparations, a significant part of the viral sequences in the carcinoma was present as oligomers, at least part of them being concatemers as shown by S1 digest. The human papillomavirus 5 subtype from this carcinoma was compared with the two other carcinoma isolates described so far and proved to be rather similar.
Authors:
H Pfister; A Gassenmaier; F Nürnberger; G Stüttgen
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Publication Detail:
Type:  Case Reports; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cancer research     Volume:  43     ISSN:  0008-5472     ISO Abbreviation:  Cancer Res.     Publication Date:  1983 Mar 
Date Detail:
Created Date:  1983-04-07     Completed Date:  1983-04-07     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  2984705R     Medline TA:  Cancer Res     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1436-41     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Animals
Bowen's Disease / genetics
DNA, Viral / analysis*
Humans
Male
Molecular Weight
Papillomaviridae / genetics*
Skin Neoplasms / genetics,  microbiology*
Tumor Virus Infections / complications,  genetics,  microbiology*
Warts / complications*,  genetics
Chemical
Reg. No./Substance:
0/DNA, Viral

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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